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The Nuclear Progesterone Receptor Reduces Post-Sigh Apneas during Sleep and Increases the Ventilatory Response to Hypercapnia in Adult Female Mice

We tested the hypothesis that the nuclear progesterone receptor (nPR) is involved in respiratory control and mediates the respiratory stimulant effect of progesterone. Adult female mice carrying a mutation in the nPR gene (PRKO mice) and wild-type controls (WT) were implanted with an osmotic pump de...

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Detalhes bibliográficos
Main Authors: Marcouiller, François, Boukari, Ryma, Laouafa, Sofien, Lavoie, Raphaël, Joseph, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063764/
https://ncbi.nlm.nih.gov/pubmed/24945655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100421
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