NOTCH Signaling in Aortic Valve Development and Calcific Aortic Valve Disease

NOTCH intercellular signaling mediates the communications between adjacent cells involved in multiple biological processes essential for tissue morphogenesis and homeostasis. The NOTCH1 mutations are the first identified human genetic variants that cause congenital bicuspid aortic valve (BAV) and ca...

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Publicado en:Front Cardiovasc Med
Autores principales: Wang, Yidong, Fang, Yuan, Lu, Pengfei, Wu, Bingruo, Zhou, Bin
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259786/
https://ncbi.nlm.nih.gov/pubmed/34239905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2021.682298
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