Notch-Tnf signalling is required for development and homeostasis of arterial valves

AIMS: Congenital anomalies of arterial valves are common birth defects, leading to valvar stenosis. With no pharmaceutical treatment that can prevent the disease progression, prosthetic replacement is the only choice of treatment, incurring considerable morbidity and mortality. Animal models present...

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Dettagli Bibliografici
Pubblicato in:Eur Heart J
Autori principali: Wang, Yidong, Wu, Bingruo, Farrar, Emily, Lui, Wendy, Lu, Pengfei, Zhang, Donghong, Alfieri, Christina M., Mao, Kai, Chu, Ming, Yang, Di, Xu, Di, Rauchman, Michael, Taylor, Verdon, Conway, Simon J., Yutzey, Katherine E., Butcher, Jonathan T., Zhou, Bin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
Soggetti:
Basic Science
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837252/
https://ncbi.nlm.nih.gov/pubmed/26491108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehv520
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