Notch-Tnf signalling is required for development and homeostasis of arterial valves

AIMS: Congenital anomalies of arterial valves are common birth defects, leading to valvar stenosis. With no pharmaceutical treatment that can prevent the disease progression, prosthetic replacement is the only choice of treatment, incurring considerable morbidity and mortality. Animal models present...

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Bibliographic Details
Published in:Eur Heart J
Main Authors: Wang, Yidong, Wu, Bingruo, Farrar, Emily, Lui, Wendy, Lu, Pengfei, Zhang, Donghong, Alfieri, Christina M., Mao, Kai, Chu, Ming, Yang, Di, Xu, Di, Rauchman, Michael, Taylor, Verdon, Conway, Simon J., Yutzey, Katherine E., Butcher, Jonathan T., Zhou, Bin
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Basic Science
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837252/
https://ncbi.nlm.nih.gov/pubmed/26491108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehv520
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