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Deletion of Myeloid Interferon Regulatory Factor 4 (Irf4) in Mouse Model Protects against Kidney Fibrosis after Ischemic Injury by Decreased Macrophage Recruitment and Activation

BACKGROUND: AKI is characterized by abrupt and reversible kidney dysfunction, and incomplete recovery leads to chronic kidney injury. Previous studies by us and others have indicated that macrophage infiltration and polarization play key roles in recovery from AKI. The role in AKI recovery played by...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Sasaki, Kensuke, Terker, Andrew S., Pan, Yu, Li, Zhilian, Cao, Shirong, Wang, Yinqiu, Niu, Aolei, Wang, Suwan, Fan, Xiaofeng, Zhang, Ming-Zhi, Harris, Raymond C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259665/
https://ncbi.nlm.nih.gov/pubmed/33619052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020071010
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