Podocyte EGFR Inhibits Autophagy Through Upregulation of Rubicon in Type 2 Diabetic Nephropathy

Renal epidermal growth factor receptor (EGFR) signaling is activated in models of diabetic nephropathy (DN), and inhibition of the EGFR signaling pathway protects against the development of DN. We have now determined that in cultured podocytes, high glucose led to increases in activation of EGFR sig...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Li, Yan, Pan, Yu, Cao, Shirong, Sasaki, Kensuke, Wang, Yinqiu, Niu, Aolei, Fan, Xiaofeng, Wang, Suwan, Zhang, Ming-Zhi, Harris, Raymond C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2021
Assuntos:
Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7881855/
https://ncbi.nlm.nih.gov/pubmed/33239448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db20-0660
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