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The Basolateral Polarity Module Promotes Slit Diaphragm Formation in Drosophila Nephrocytes, a Model of Vertebrate Podocytes

BACKGROUND: Podocyte slit diaphragms (SDs) are intercellular junctions that function as size-selective filters, excluding most proteins from urine. Abnormalities in SDs cause proteinuria and nephrotic syndrome. Podocytes exhibit apicobasal polarity, which can affect fundamental aspects of cell biolo...

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Dettagli Bibliografici
Pubblicato in:J Am Soc Nephrol
Autori principali: Mysh, Michael, Poulton, John S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259641/
https://ncbi.nlm.nih.gov/pubmed/33795424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020071050
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