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Sns and Kirre, the Drosophila orthologs of Nephrin and Neph1, direct adhesion, fusion and formation of a slit diaphragm-like structure in insect nephrocytes

The Immunoglobulin superfamily (IgSF) proteins Neph1 and Nephrin are co-expressed within podocytes in the kidney glomerulus, where they localize to the slit diaphragm (SD) and contribute to filtration between blood and urine. Herein, we demonstrate that their Drosophila orthologs Kirre (Duf) and Sns...

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Detalhes bibliográficos
Main Authors: Zhuang, Shufei, Shao, Huanjie, Guo, Fengli, Trimble, Rhonda, Pearce, Elspeth, Abmayr, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729346/
https://ncbi.nlm.nih.gov/pubmed/19515699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.031609
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