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Exocyst Genes Are Essential for Recycling Membrane Proteins and Maintaining Slit Diaphragm in Drosophila Nephrocytes

BACKGROUND: Studies have linked mutations in genes encoding the eight-protein exocyst protein complex to kidney disease, but the underlying mechanism is unclear. Because Drosophila nephrocytes share molecular and structural features with mammalian podocytes, they provide an efficient model for study...

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Foilsithe in:J Am Soc Nephrol
Main Authors: Wen, Pei, Zhang, Fujian, Fu, Yulong, Zhu, Jun-yi, Han, Zhe
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Nephrology 2020
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217423/
https://ncbi.nlm.nih.gov/pubmed/32238475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019060591
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