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Synaptojanin1 deficiency upregulates basal autophagosome formation in astrocytes

Macroautophagy dysregulation is implicated in multiple neurological disorders, such as Parkinson's disease. While autophagy pathways are heavily researched in heterologous cells and neurons, regulation of autophagy in the astrocyte, the most abundant cell type in the mammalian brain, is less we...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Pan, Ping-Yue, Zhu, Justin, Rizvi, Asma, Zhu, Xinyu, Tanaka, Hikari, Dreyfus, Cheryl F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8258991/
https://ncbi.nlm.nih.gov/pubmed/34126070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100873
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