H3K27 demethylases are dispensable for activation of Polycomb-regulated injury response genes in peripheral nerve

The induction of nerve injury response genes in Schwann cells depends on both transcriptional and epigenomic reprogramming. The nerve injury response program is regulated by the repressive histone mark H3K27 trimethylation (H3K27me3), deposited by Polycomb repressive complex 2 (PRC2). Loss of PRC2 f...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Duong, Phu, Ma, Ki H., Ramesh, Raghu, Moran, John J., Won, Seongsik, Svaren, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8258988/
https://ncbi.nlm.nih.gov/pubmed/34090875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100852
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