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H3K27 demethylases are dispensable for activation of Polycomb-regulated injury response genes in peripheral nerve
The induction of nerve injury response genes in Schwann cells depends on both transcriptional and epigenomic reprogramming. The nerve injury response program is regulated by the repressive histone mark H3K27 trimethylation (H3K27me3), deposited by Polycomb repressive complex 2 (PRC2). Loss of PRC2 f...
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| Publicado en: | J Biol Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8258988/ https://ncbi.nlm.nih.gov/pubmed/34090875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100852 |
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