H3K27 demethylases are dispensable for activation of Polycomb-regulated injury response genes in peripheral nerve

The induction of nerve injury response genes in Schwann cells depends on both transcriptional and epigenomic reprogramming. The nerve injury response program is regulated by the repressive histone mark H3K27 trimethylation (H3K27me3), deposited by Polycomb repressive complex 2 (PRC2). Loss of PRC2 f...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Duong, Phu, Ma, Ki H., Ramesh, Raghu, Moran, John J., Won, Seongsik, Svaren, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8258988/
https://ncbi.nlm.nih.gov/pubmed/34090875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100852
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