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An in silico Framework of Cartilage Degeneration That Integrates Fibril Reorientation and Degradation Along With Altered Hydration and Fixed Charge Density Loss

Injurious mechanical loading of articular cartilage and associated lesions compromise the mechanical and structural integrity of joints and contribute to the onset and progression of cartilage degeneration leading to osteoarthritis (OA). Despite extensive in vitro and in vivo research, it remains un...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Elahi, Seyed Ali, Tanska, Petri, Korhonen, Rami K., Lories, Rik, Famaey, Nele, Jonkers, Ilse
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8258121/
https://ncbi.nlm.nih.gov/pubmed/34239859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2021.680257
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