Exploiting the reactive oxygen species imbalance in high-risk paediatric acute lymphoblastic leukaemia through auranofin

BACKGROUND: The prognosis for high-risk childhood acute leukaemias remains dismal and established treatment protocols often cause long-term side effects in survivors. This study aims to identify more effective and safer therapeutics for these patients. METHODS: A high-throughput phenotypic screen of...

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Dades bibliogràfiques
Publicat a:Br J Cancer
Autors principals: Karsa, Mawar, Kosciolek, Angelika, Bongers, Angelika, Mariana, Anna, Failes, Tim, Gifford, Andrew J., Kees, Ursula R., Cheung, Laurence C., Kotecha, Rishi S., Arndt, Greg M., Haber, Michelle, Norris, Murray D., Sutton, Rosemary, Lock, Richard B., Henderson, Michelle J., Somers, Klaartje
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8257682/
https://ncbi.nlm.nih.gov/pubmed/33837299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-021-01332-x
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