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Arsenic trioxide and auranofin inhibit selenoprotein synthesis: implications for chemotherapy for acute promyelocytic leukaemia
BACKGROUND AND PURPOSE: Arsenicals have been used medicinally for decades to treat both infectious disease and cancer. Arsenic trioxide (As(2)O(3)) is effective for treatment of acute promyelocytic leukaemia (APL), yet the mechanism of action of this drug is still widely debated. Recently, As(2)O(3)...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2451042/ https://ncbi.nlm.nih.gov/pubmed/18587442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.161 |
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