A miRNA signature predicts benefit from addition of hypoxia-modifying therapy to radiation treatment in invasive bladder cancer

BACKGROUND: miRNAs are promising biomarkers in oncology as their small size makes them less susceptible to degradation than mRNA in FFPE tissue. We aimed to derive a hypoxia-associated miRNA signature for bladder cancer. METHODS: Taqman miRNA array cards identified miRNA seed genes induced under hyp...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Khan, Mairah T., Irlam-Jones, Joely J., Pereira, Ronnie Rodrigues, Lane, Brian, Valentine, Helen R., Aragaki, Kai, Dyrskjøt, Lars, McConkey, David J., Hoskin, Peter J., Choudhury, Ananya, West, Catharine M. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8257670/
https://ncbi.nlm.nih.gov/pubmed/33846523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-021-01326-9
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