Expression of hypoxia-inducible factor-1α predicts benefit from hypoxia modification in invasive bladder cancer

BACKGROUND: The addition of carbogen and nicotinamide (CON) to radiotherapy (RT) improves overall survival in invasive bladder cancer. We explored whether expression of the hypoxia marker hypoxia-inducible factor-1α (HIF-1α) alone or in combination with other markers predicted benefit from CON. METH...

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Autori principali: Hunter, B A, Eustace, A, Irlam, J J, Valentine, H R, Denley, H, Oguejiofor, K K, Swindell, R, Hoskin, P J, Choudhury, A, West, C M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
Soggetti:
Clinical Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119984/
https://ncbi.nlm.nih.gov/pubmed/24937673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.315
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