Enzymatic methyl sequencing detects DNA methylation at single-base resolution from picograms of DNA

Bisulfite sequencing detects 5mC and 5hmC at single-base resolution. However, bisulfite treatment damages DNA, which results in fragmentation, DNA loss, and biased sequencing data. To overcome these problems, enzymatic methyl-seq (EM-seq) was developed. This method detects 5mC and 5hmC using two set...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Genome Res
Autors principals: Vaisvila, Romualdas, Ponnaluri, V.K. Chaithanya, Sun, Zhiyi, Langhorst, Bradley W., Saleh, Lana, Guan, Shengxi, Dai, Nan, Campbell, Matthew A., Sexton, Brittany S., Marks, Katherine, Samaranayake, Mala, Samuelson, James C., Church, Heidi E., Tamanaha, Esta, Corrêa, Ivan R., Pradhan, Sriharsa, Dimalanta, Eileen T., Evans, Thomas C., Williams, Louise, Davis, Theodore B.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2021
Matèries:
Method
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8256858/
https://ncbi.nlm.nih.gov/pubmed/34140313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.266551.120
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars