A highly conserved pocket on PP2A‐B56 is required for hSgo1 binding and cohesion protection during mitosis

The shugoshin proteins are universal protectors of centromeric cohesin during mitosis and meiosis. The binding of human hSgo1 to the PP2A‐B56 phosphatase through a coiled‐coil (CC) region mediates cohesion protection during mitosis. Here we undertook a structure function analysis of the PP2A‐B56‐hSg...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Ueki, Yumi, Hadders, Michael A, Weisser, Melanie B, Nasa, Isha, Sotelo‐Parrilla, Paula, Cressey, Lauren E, Gupta, Tanmay, Hertz, Emil P T, Kruse, Thomas, Montoya, Guillermo, Jeyaprakash, A Arockia, Kettenbach, Arminja, Lens, Susanne M A, Nilsson, Jakob
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8256288/
https://ncbi.nlm.nih.gov/pubmed/33973335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202052295
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados