HLA-dependent heterogeneity and macrophage immunoproteasome activation during lung COVID-19 disease

BACKGROUND: The worldwide pandemic caused by the SARS-CoV-2 virus is characterized by significant and unpredictable heterogeneity in symptoms that remains poorly understood. METHODS: Transcriptome and single cell transcriptome of COVID19 lung were integrated with deeplearning analysis of MHC class I...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Desterke, Christophe, Turhan, Ali G., Bennaceur-Griscelli, Annelise, Griscelli, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8256232/
https://ncbi.nlm.nih.gov/pubmed/34225749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-021-02965-5
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