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PPARγ Cistrome Repression during Activation of Lung Monocyte-Macrophages in Severe COVID-19

The molecular mechanisms of cytokine storm in patients with severe COVID-19 infections are poorly understood. To uncover these events, we performed transcriptome analyses of lung biopsies from patients with COVID-19, revealing a gene enrichment pattern similar to that of PPARγ-knockout macrophages....

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I publikationen:iScience
Huvudupphovsmän: Desterke, Christophe, Turhan, Ali G., Bennaceur-Griscelli, Annelise, Griscelli, Frank
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518203/
https://ncbi.nlm.nih.gov/pubmed/33015591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101611
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