Detection of Hematopoietic Stem Cell Transcriptome in Human Fetal Kidneys and Kidney Organoids Derived From Human Induced Pluripotent Stem Cells

BACKGROUND: In mammalians, hematopoietic stem cells (HSCs) arise in the dorsal aorta from the hemogenic endothelium, followed by their migration to the fetal liver and to the bone marrow. In zebrafish, the kidney is the site of primary hematopoiesis. In humans, the presence of HSCs in the fetal or a...

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Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Hwang, Jin Wook, Desterke, Christophe, Loisel-Duwattez, Julien, Griscelli, Frank, Bennaceur-Griscelli, Annelise, Turhan, Ali G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8226023/
https://ncbi.nlm.nih.gov/pubmed/34178994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.668833
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