APPsα rescues impaired Ca(2+) homeostasis in APP- and APLP2-deficient hippocampal neurons

Alterations in Ca(2+) homeostasis have been reported in several in vitro and in vivo studies using mice expressing the Alzheimer’s disease–associated transgenes, presenilin and the amyloid precursor protein (APP). While intense research focused on amyloid-β–mediated functions on neuronal Ca(2+) hand...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Ludewig, Susann, Herrmann, Ulrike, Michaelsen-Preusse, Kristin, Metzdorf, Kristin, Just, Jennifer, Bold, Charlotte, Müller, Ulrike C., Korte, Martin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2021
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8256088/
https://ncbi.nlm.nih.gov/pubmed/34172567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011506118
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