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APPsα rescues impaired Ca(2+) homeostasis in APP- and APLP2-deficient hippocampal neurons
Alterations in Ca(2+) homeostasis have been reported in several in vitro and in vivo studies using mice expressing the Alzheimer’s disease–associated transgenes, presenilin and the amyloid precursor protein (APP). While intense research focused on amyloid-β–mediated functions on neuronal Ca(2+) hand...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8256088/ https://ncbi.nlm.nih.gov/pubmed/34172567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011506118 |
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