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Agmatine requires GluN2B-containing NMDA receptors to inhibit the development of neuropathic pain
A decarboxylated form of L-arginine, agmatine, preferentially antagonizes NMDArs containing Glun2B subunits within the spinal cord and lacks motor side effects commonly associated with non-subunit-selective NMDAr antagonism, namely sedation and motor impairment. Spinally delivered agmatine has been...
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| Publicado no: | Mol Pain |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8255568/ https://ncbi.nlm.nih.gov/pubmed/34210178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/17448069211029171 |
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