Agmatine preferentially antagonizes GluN2B-containing N-methyl-d-aspartate receptors in spinal cord

The role of the N-methyl-d-aspartate receptor (NMDAr) as a contributor to maladaptive neuroplasticity underlying the maintenance of chronic pain is well established. Agmatine, an NMDAr antagonist, has been shown to reverse tactile hypersensitivity in rodent models of neuropathic pain while lacking t...

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Detalhes bibliográficos
Publicado no:J Neurophysiol
Main Authors: Waataja, Jonathan J., Peterson, Cristina D., Verma, Harsha, Goracke-Postle, Cory J., Séguéla, Philippe, Delpire, Eric, Wilcox, George L., Fairbanks, Carolyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397392/
https://ncbi.nlm.nih.gov/pubmed/30427758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00172.2018
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