Agmatine preferentially antagonizes GluN2B-containing N-methyl-d-aspartate receptors in spinal cord

The role of the N-methyl-d-aspartate receptor (NMDAr) as a contributor to maladaptive neuroplasticity underlying the maintenance of chronic pain is well established. Agmatine, an NMDAr antagonist, has been shown to reverse tactile hypersensitivity in rodent models of neuropathic pain while lacking t...

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Detaylı Bibliyografya
Yayımlandı:J Neurophysiol
Asıl Yazarlar: Waataja, Jonathan J., Peterson, Cristina D., Verma, Harsha, Goracke-Postle, Cory J., Séguéla, Philippe, Delpire, Eric, Wilcox, George L., Fairbanks, Carolyn A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397392/
https://ncbi.nlm.nih.gov/pubmed/30427758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00172.2018
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