NGMA-6. Quantitative MGMT Promoter Methylation Index Indicates Non-Linear, Prognostic Effect in Glioblastoma

BACKGROUND: Epigenetic inhibition of the O6-methylguanine-DNA-methyltransferase (MGMT) gene has emerged as a clinically relevant prognostic marker in glioblastoma (GBM). Methylation of the MGMT promoter has been shown to increase chemotherapy efficacy. While traditionally reported as a binary marker...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Neurooncol Adv
Autori principali: Gibson, David, Ravi, Akshay, Rodriguez, Eduardo, Chang, Susan, Bush, Nancy, Taylor, Jennie, Clarke, Jennifer, Solomon, David, Scheffler, Aaron, Witte, John, Okada, Hideho, Berger, Mitchel, Chehab, Farid, Butowski, Nicholas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
Soggetti:
Supplement Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8255458/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab070.021
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi