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OTME-17. Single cell characterization of the immune microenvironment of melanoma brain and leptomeningeal metastases

Melanoma brain metastases (MBM) and leptomeningeal metastases (LMM) are two manifestations of melanoma dissemination to the CNS with vastly different survival outcomes. Analysis of single cell RNA-Seq data from 43 clinical specimens has uncovered a distinct, immune-suppressed T cell landscape in the...

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Bibliografiska uppgifter
I publikationen:Neurooncol Adv
Huvudupphovsmän: Smalley, Inna, Chen, Zhihua, Phadke, Manali, Li, Jiannong, Yu, Xiaoqing, Wyatt, Clayton, Evernden, Brittany, Messina, Jane, Sarnaik, Amod, Sondak, Vernon, Zhang, Chaomei, Law, Vincent, Tran, Nam, Etame, Arnold, Macaulay, Robert, Eroglu, Zeynep, Forsyth, Peter, Rodriguez, Paulo, Chen, Ann, Smalley, Keiran
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8255427/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab070.068
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