TMOD-02. IN VITRO & IN VIVO CULTURE OF PATIENT DERIVED (PD) CSF-CTCS IN LEPTOMENINGEAL DISEASE (LMD) FROM MELANOMA TO IDENTIFY NOVEL TREATMENT STRATEGIES

BACKGROUND: Approx. 5% of melanoma pts develop LMD. There are essentially no models of LMD available for therapeutic development. A significant barrier to the development of effective therapies against LMD has been the inability to culture and expand LMD cells. Here we report our strategies to in vi...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Law, Vincent, Evernden, Brittany, Puskas, John, Caceres, Gisela, Ryzhova, Elena, Smalley, Inna, Tran, Nam, Etame, Arnold, Magliocco, Anthony, Smalley, Keiran, Forsyth, Peter
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
Assuntos:
Tumor Models
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651062/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.953
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