EXTH-39. DETECTION, MOLECULAR PROFILING AND CULTURE OF CSF-CTCs IN LEPTOMENINGEAL DISEASE (LMDz) IN MELANOMA TO IMPROVE DIAGNOSIS AND TREATMENT STRATEGIES

BACKGROUND: Approximately 5% of melanoma-associated brain metastasis also develops universally fatal LMDz. The aim of this study was to improve diagnosis and personalized treatment for melanoma-LMDz by enumerating CTCs from CSF. METHODS: CSF-CTCs were enriched and detected by Veridex CellSearch® Sys...

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Publicado en:Neuro Oncol
Autores principales: Law, Vincent, Evernden, Brittany, Kenchappa, Rajappa, Puskas, John, Ryzhova, Elena, Smalley, Inna, Tran, Nam, Etame, Arnold, Sahebjam, Solmaz, Magliocco, Anthony, Smalley, Keiran, Forsyth, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217324/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.387
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