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Combinatorial patterns of graded RhoA activation and uniform F-actin depletion promote tissue curvature

During development, gene expression regulates cell mechanics and shape to sculpt tissues. Epithelial folding proceeds through distinct cell shape changes that occur simultaneously in different regions of a tissue. Here, using quantitative imaging in Drosophila melanogaster, we investigate how patter...

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Détails bibliographiques
Publié dans:Development
Auteurs principaux: Denk-Lobnig, Marlis, Totz, Jan F., Heer, Natalie C., Dunkel, Jörn, Martin, Adam C.
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8254875/
https://ncbi.nlm.nih.gov/pubmed/34124762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.199232
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