HectD1 Controls Hematopoietic Stem Cell Regeneration by Coordinating Ribosome Assembly and Protein Synthesis

Impaired ribosome function is the underlying etiology in a group of bone marrow failure syndromes called ribosomopathies. However, how ribosomes are regulated remains poorly understood, as are approaches to restore hematopoietic stem cell (HSC) function attributable to defective ribosome biogenesis....

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Bibliografske podrobnosti
izdano v:Cell Stem Cell
Main Authors: Lv, Kaosheng, Gong, Chujie, Antony, Charles, Han, Xu, Ren, Jian-Gang, Donaghy, Ryan, Cheng, Ying, Pellegrino, Simone, Warren, Alan J., Paralkar, Vikram R., Tong, Wei
Format: Artigo
Jezik:Inglês
Izdano: 2021
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8254759/
https://ncbi.nlm.nih.gov/pubmed/33711283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2021.02.008
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