HectD1 Controls Hematopoietic Stem Cell Regeneration by Coordinating Ribosome Assembly and Protein Synthesis

Impaired ribosome function is the underlying etiology in a group of bone marrow failure syndromes called ribosomopathies. However, how ribosomes are regulated remains poorly understood, as are approaches to restore hematopoietic stem cell (HSC) function attributable to defective ribosome biogenesis....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Stem Cell
Egile Nagusiak: Lv, Kaosheng, Gong, Chujie, Antony, Charles, Han, Xu, Ren, Jian-Gang, Donaghy, Ryan, Cheng, Ying, Pellegrino, Simone, Warren, Alan J., Paralkar, Vikram R., Tong, Wei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8254759/
https://ncbi.nlm.nih.gov/pubmed/33711283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2021.02.008
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