Loading...
The aminosterol Claramine inhibits β-secretase 1–mediated insulin receptor cleavage
The cleavage of the insulin receptor by β-secretase 1 (BACE1) in the liver increases during diabetes, which contributes to reduce insulin receptor levels and impair insulin signaling. However, the precise signaling events that lead to this increased cleavage are unclear. We showed that BACE1 cleaves...
Na minha lista:
| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2021
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8254121/ https://ncbi.nlm.nih.gov/pubmed/34029592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100818 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|