Tribbles homolog 3-mediated targeting the AKT/mTOR axis in mice with retinal degeneration

Various retinal degenerative disorders manifest in alterations of the AKT/mTOR axis. Despite this, consensus on the therapeutic targeting of mTOR in degenerating retinas has not yet been achieved. Therefore, we investigated the role of AKT/mTOR signaling in rd16 retinas, in which we restored the AKT...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Saltykova, Irina V., Elahi, Asif, Pitale, Priyam M., Gorbatyuk, Oleg S., Athar, Mohammad, Gorbatyuk, Marina S.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253859/
https://ncbi.nlm.nih.gov/pubmed/34215725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03944-w
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