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Translational attenuation and retinal degeneration in mice with an active integrated stress response
An integrated stress response (ISR), identified in several different animal models of inherited retinal degeneration (IRD), is activated following various cellular stresses. The ISR results in the phosphorylation of eIF2α (p-eIF2α) and a consequent halt in protein synthesis. Although generally prote...
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| Publicado no: | Cell Death Dis |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5924758/ https://ncbi.nlm.nih.gov/pubmed/29706649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0513-1 |
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