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Translational attenuation and retinal degeneration in mice with an active integrated stress response
An integrated stress response (ISR), identified in several different animal models of inherited retinal degeneration (IRD), is activated following various cellular stresses. The ISR results in the phosphorylation of eIF2α (p-eIF2α) and a consequent halt in protein synthesis. Although generally prote...
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| 出版年: | Cell Death Dis |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5924758/ https://ncbi.nlm.nih.gov/pubmed/29706649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0513-1 |
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