Redirected nuclear glutamate dehydrogenase supplies Tet3 with α-ketoglutarate in neurons

Tet3 is the main α-ketoglutarate (αKG)-dependent dioxygenase in neurons that converts 5-methyl-dC into 5-hydroxymethyl-dC and further on to 5-formyl- and 5-carboxy-dC. Neurons possess high levels of 5-hydroxymethyl-dC that further increase during neural activity to establish transcriptional plastici...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nat Commun
मुख्य लेखकों: Traube, Franziska R., Özdemir, Dilara, Sahin, Hanife, Scheel, Constanze, Glück, Andrea F., Geserich, Anna S., Oganesian, Sabine, Kostidis, Sarantos, Iwan, Katharina, Rahimoff, René, Giorgio, Grazia, Müller, Markus, Spada, Fabio, Biel, Martin, Cox, Jürgen, Giera, Martin, Michalakis, Stylianos, Carell, Thomas
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2021
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253819/
https://ncbi.nlm.nih.gov/pubmed/34215750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24353-9
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन