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Chronic glucocorticoid treatment induces hepatic lipid accumulation and hyperinsulinaemia in part through actions on AgRP neurons

Glucocorticoids (GCs) are widely prescribed anti-inflammatory medicines, but their use can lead to metabolic side-effects. These may occur through direct actions of GCs on peripheral organs, but could also be mediated by the hypothalamic AgRP neurons, which can increase food intake and modify periph...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Harno, Erika, Sefton, Charlotte, Wray, Jonathan R., Allen, Tiffany-Jayne, Davies, Alison, Coll, Anthony P., White, Anne
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253818/
https://ncbi.nlm.nih.gov/pubmed/34215821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-93378-3
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