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NAD(P)HX epimerase downregulation promotes tumor progression through ROS/HIF‐1α signaling in hepatocellular carcinoma

Reactive oxygen species (ROS) derived from aberrant tumor metabolism could contribute to tumor invasion and metastasis. NAD(P)HX Epimerase (NAXE), an epimerase that allows the repair of damaged forms of antioxidant NADPH, is a potential cellular ROS scavenger and its role in tumor development is sti...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Sun, Bo, Yu, Lei, Xu, Cong, Li, Yi‐Ming, Zhao, Yan‐Rong, Cao, Mo‐Mo, Yang, Lian‐Yue
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253267/
https://ncbi.nlm.nih.gov/pubmed/33932069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14925
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