Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases

The epigenomic regulation of transcriptional programs in metastatic prostate cancer is poorly understood. We studied the epigenomic landscape of prostate cancer drivers using transcriptional profiling and ChIP‐seq in four clonal metastatic tumors derived from a single prostate cancer patient. Our ep...

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Pubblicato in:Mol Oncol
Autori principali: Severson, Tesa M., Zhu, Yanyun, De Marzo, Angelo M., Jones, Tracy, Simons, Jonathan W., Nelson, William G., Yegnasubramanian, Srinivasan, Freedman, Matthew L., Wessels, Lodewyk, Bergman, Andries M., Haffner, Michael C., Zwart, Wilbert
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253095/
https://ncbi.nlm.nih.gov/pubmed/33576154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12923
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