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Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases

The epigenomic regulation of transcriptional programs in metastatic prostate cancer is poorly understood. We studied the epigenomic landscape of prostate cancer drivers using transcriptional profiling and ChIP‐seq in four clonal metastatic tumors derived from a single prostate cancer patient. Our ep...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Severson, Tesa M., Zhu, Yanyun, De Marzo, Angelo M., Jones, Tracy, Simons, Jonathan W., Nelson, William G., Yegnasubramanian, Srinivasan, Freedman, Matthew L., Wessels, Lodewyk, Bergman, Andries M., Haffner, Michael C., Zwart, Wilbert
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253095/
https://ncbi.nlm.nih.gov/pubmed/33576154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12923
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