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Malaria Pigment Crystals: The Achilles′ Heel of the Malaria Parasite

The biogenic formation of hemozoin crystals, a crucial process in heme detoxification by the malaria parasite, is reviewed as an antimalarial drug target. We first focus on the in‐vivo formation of hemozoin. A model is presented, based on native‐contrast 3D imaging obtained by X‐ray and electron mic...

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Bibliografske podrobnosti
izdano v:ChemMedChem
Main Authors: Kapishnikov, Sergey, Hempelmann, Ernst, Elbaum, Michael, Als‐Nielsen, Jens, Leiserowitz, Leslie
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252759/
https://ncbi.nlm.nih.gov/pubmed/33523575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.202000895
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