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Malaria Pigment Crystals: The Achilles′ Heel of the Malaria Parasite
The biogenic formation of hemozoin crystals, a crucial process in heme detoxification by the malaria parasite, is reviewed as an antimalarial drug target. We first focus on the in‐vivo formation of hemozoin. A model is presented, based on native‐contrast 3D imaging obtained by X‐ray and electron mic...
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| Pubblicato in: | ChemMedChem |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8252759/ https://ncbi.nlm.nih.gov/pubmed/33523575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.202000895 |
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