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Unraveling heme detoxification in the malaria parasite by in situ correlative X-ray fluorescence microscopy and soft X-ray tomography

A key drug target for malaria has been the detoxification pathway of the iron-containing molecule heme, which is the toxic byproduct of hemoglobin digestion. The cornerstone of heme detoxification is its sequestration into hemozoin crystals, but how this occurs remains uncertain. We report new resul...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Kapishnikov, Sergey, Grolimund, Daniel, Schneider, Gerd, Pereiro, Eva, McNally, James G., Als-Nielsen, Jens, Leiserowitz, Leslie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548722/
https://ncbi.nlm.nih.gov/pubmed/28790371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06650-w
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