Classification of high‐grade cervical intraepithelial neoplasia by p16(ink4a), Ki‐67, HPV E4 and FAM19A4/miR124‐2 methylation status demonstrates considerable heterogeneity with potential consequences for management

High‐grade cervical intraepithelial neoplasia (CIN2 and CIN3) represents a heterogeneous disease with varying cancer progression risks. Biomarkers indicative for a productive human papillomavirus (HPV) infection (HPV E4) and a transforming HPV infection (p16(ink4a), Ki‐67 and host‐cell DNA methylati...

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Detaylı Bibliyografya
Yayımlandı:Int J Cancer
Asıl Yazarlar: Vink, Frederique J., Dick, Stèfanie, Heideman, Daniëlle A. M., De Strooper, Lise M. A., Steenbergen, Renske D. M., Lissenberg‐Witte, Birgit I., Floore, Arno, Bonde, Jesper H., Oštrbenk Valenčak, Anja, Poljak, Mario, Petry, Karl U., Hillemanns, Peter, van Trommel, Nienke E., Berkhof, Johannes, Bleeker, Maaike C. G., Meijer, Chris J. L. M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley & Sons, Inc. 2021
Konular:
Tumor Markers and Signatures
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252755/
https://ncbi.nlm.nih.gov/pubmed/33729551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.33566
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