Načítá se...
A Box of Chemistry to Inhibit the MEN1 Tumor Suppressor Gene Promoting Leukemia
Targeting protein‐protein interactions (PPIs) with small‐molecule inhibitors has become a hotbed of modern drug development. In this review, we describe a new class of PPI inhibitors that block menin from binding to MLL proteins. Menin is encoded by the MEN1 tumor suppressor, but acts as an essentia...
Uloženo v:
| Vydáno v: | ChemMedChem |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
John Wiley and Sons Inc.
2021
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8252030/ https://ncbi.nlm.nih.gov/pubmed/33534953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.202000972 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|