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Targeting TRIM Proteins: A Quest towards Drugging an Emerging Protein Class

The ubiquitylation machinery regulates several fundamental biological processes from protein homeostasis to a wide variety of cellular signaling pathways. As a consequence, its dysregulation is linked to diseases including cancer, neurodegeneration, and autoimmunity. With this review, we aim to high...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: D'Amico, Francesca, Mukhopadhyay, Rishov, Ovaa, Huib, Mulder, Monique P. C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8251876/
https://ncbi.nlm.nih.gov/pubmed/33482040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000787
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