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Computational analysis of membrane proteins: the largest class of drug targets

Given the key roles of integral membrane proteins as transporters and channels, it is necessary to understand their structures and, hence, mechanisms and regulation at the molecular level. Membrane proteins represent ~30% of all proteins of currently sequenced genomes. Paradoxically, however, only ~...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Arinaminpathy, Yalini, Khurana, Ekta, Engelman, Donald M., Gerstein, Mark B.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2009
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796609/
https://ncbi.nlm.nih.gov/pubmed/19733256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2009.08.006
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