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Computational analysis of membrane proteins: the largest class of drug targets

Given the key roles of integral membrane proteins as transporters and channels, it is necessary to understand their structures and, hence, mechanisms and regulation at the molecular level. Membrane proteins represent ~30% of all proteins of currently sequenced genomes. Paradoxically, however, only ~...

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Hlavní autoři: Arinaminpathy, Yalini, Khurana, Ekta, Engelman, Donald M., Gerstein, Mark B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796609/
https://ncbi.nlm.nih.gov/pubmed/19733256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2009.08.006
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