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Computational analysis of membrane proteins: the largest class of drug targets

Given the key roles of integral membrane proteins as transporters and channels, it is necessary to understand their structures and, hence, mechanisms and regulation at the molecular level. Membrane proteins represent ~30% of all proteins of currently sequenced genomes. Paradoxically, however, only ~...

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Sonraí Bibleagrafaíochta
Main Authors: Arinaminpathy, Yalini, Khurana, Ekta, Engelman, Donald M., Gerstein, Mark B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796609/
https://ncbi.nlm.nih.gov/pubmed/19733256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2009.08.006
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