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Enantioselective [2 + 2] Photocycloaddition via Iminium Ions: Catalysis by a Sensitizing Chiral Brønsted Acid

[Image: see text] N,O-Acetals derived from α,β-unsaturated β-aryl substituted aldehydes and (1-aminocyclohexyl)methanol were found to undergo a catalytic enantioselective [2 + 2] photocycloaddition to a variety of olefins (19 examples, 54–96% yield, 84–98% ee). The reaction was performed by visible...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Pecho, Franziska, Sempere, Yeshua, Gramüller, Johannes, Hörmann, Fabian M., Gschwind, Ruth M., Bach, Thorsten
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8251699/
https://ncbi.nlm.nih.gov/pubmed/34156845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.1c05240
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